Progress on the discovery and development of anti-zika virus agents / 药学学报

Zika virus (ZIKV) is a kind of mosquito-borne flavivirus. ZIKV infection initially shows mild symptoms on patients, but will lead to severe neurological complications (such as Guillain-Barré syndrome) in the end. Meanwhile, pregnant women are sensitive to ZIKV, since the viruses may cause microcephaly. In 2015, after the epidemic in Brazil, ZIKV draws the public attention around the world because of its increased virulence and rapid dissemination. However, there is no approved specific anti-ZIKV drugs at present. This review summarizes progress on anti-zika virus drug research and provides prospects in this field.

Research progress of new anti-influenza drugs / 中华实用儿科临床杂志

Influenza virus,as the root cause of public health problems,is mainly transmitted by aerosols with high infectivity and high mortality,which seriously endangers human health.Moreover,influenza viruses mutate rapidly,and existing drugs are constantly appearing resistant,it is urgent to develop new anti-influenza drugs.Now,the anti-influenza drugs with different targets from the 2 aspects of viral targets and host targets are introduces,and focus on the research progress of new anti-influenza drugs.